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Oct retinal layers diagram1/12/2024 All cases of acute CRAO on fundus examination reveal extensive retinal whitening, presence of a cherry red spot, retinal vessel attenuation, and preservation of optic nerve head perfusion. Trial Registration Number: Not applicable.Īlbrecht von Graefes first described central retinal artery occlusion (CRAO) in 1859 as a disastrous ophthalmic emergency characterized by sudden onset, acute painless loss of vision, and a poor prognosis. More prospective studies analysing a larger number of cases at fixed time points will be required in the future. OCT in CRAO is a useful for determining the severity of retinal ischemia, disease stage, tissue damage mechanism, and final visual outcome. Regardless of the CRAO grade, the final end-point seen was inner retinal layer thinning over time. Other OCT findings in higher grades of CRAO included inner retinal fluid, neurosensory detachment, internal limiting membrane detachment, hyperreflective foci, and posterior vitreous opacities. Prominent middle limiting membrane (p-MLM) sign was seen in mild and moderate CRAO eyes while were not visualised in severe CRAO. Moderate CRAO cases had total inner retinal layer opacification, which resulted in retinal thinning over time. Middle retinal layer opacification was more common in mild CRAO cases, which caused inner retinal layer thinning over time. At presentation, the study had 11, 16, and 12 cases of mild, moderate, and severe CRAO, respectively. There were 39 eyes from 38 patients with acute CRAO who underwent 96 OCT scans. OCT scans were evaluated and classified into four-time intervals based on symptom duration. Based on the OCT findings at presentation, cases were classified into three severity groups: mild, moderate, and severe. The study included acute CRAO cases of < 7 days duration, imaged on OCT at various time points. To study the optical coherence tomography (OCT) changes in eyes with acute central retinal artery occlusion (CRAO) of different severity and at different disease stages.
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